This list of peer-reviewed publications provides additional information and context on the new studies done for the HPV Challenge Program by the petroleum industry.


The below publication is available for purchase via an external site.

An Overview of the Petroleum Industry Response to the High Production Volume Challenge Program

Potential for Repeat Dose and Dev Tox of Dermally Administered Crude and Relation to Repro Tox

The Toxicological Properties of Petroleum Gases

Tox Assessment of Heavy Straight Run Naphtha in a Repeated Dose Repro Tox Screening Test

A 13-Week Dermal Repeat-Dose Neurotoxicity Study of Hydrodesulfurized Kerosene in Rats

Characterization of the Noncancer Hazards of Gas Oils

The Toxicological Effects of Heavy Fuel Oil Category Substances

Acute Subchronic and Dev Tox Properties of Lubricating Oil Base Stocks

Subchronic and Developmental Toxicity of Aromatic Extracts

Toxicological Assessment of Green Petroleum Coke

Toxicological Assessment of Refined Naphthenic Acids in a Repeated Dose-Developmental Toxicity

Disulfide Oil Hazard Assessment Using Categorical Analysis and a Mode of Action Determination

Aquatic hazard and biodegradability of light and middle atmospheric distillate petroleum streams

Aquatic hazard assessment of a commercial sample of naphthenic acids

Assessing the mammalian toxicity of high-boiling point petroleum substances

Assessing the mammalian toxicity of high-boiling petroleum substances under the rubric of the HPV program

The development of statistical models to determine the relationship between aromatic-ring class profile and repeat-dose and developmental toxicities of high-boiling petroleum substances

Evaluating the male and female reproductive toxicity of high-boiling petroleum substances

Genetic toxicity of high-boiling point petroleum substances

Peer consultation on relationship between PAC profile and toxicity of petroleum substances

The relationship between developmental toxicity and aromatic-ring class profile of high-boiling petroleum substances

The relationship between repeat-dose toxicity and aromatic-ring class profile of high-boiling petroleum substances